Yi Guo, PhD, FAMIA
Associate Professor & Interim Chief, Division of Biomedical Informatics and Data Science
About Yi Guo
Dr. Guo is an Associate Professor and Interim Division Chief of Biomedical Informatics in the Department of Health Outcomes and Biomedical Informatics at the University of Florida. He also serves as the Director of the Cancer Informatics Shared Resource and the Associate Director of the Cancer Quantitative Sciences Division for the UF Health Cancer Center, as well as the Associate Director of the Office of Data Science Research for the OneFlorida+ Clinical Research Network.
Dr. Guo has a multi-disciplinary background in the analysis of real-world data such as those from electronic health records (EHRs) and administrative claims, randomized trial and observational study design, predictive modeling (e.g., statistical and machine learning), causal modeling, and the analysis of patient-reported outcomes (PROs).
Together, Dr. Guo’s areas of expertise serve an overarching research theme: generating real-world evidence to support healthcare decision-making for disease prevention and control. Under this overarching theme, Dr. Guo’s research areas and expertise can be divided into three key methodologies: (1) EHR-based phenotyping and risk stratification – the identification of sub-populations with certain conditions or at higher risk for diseases, (2) Causal modeling and inference – the examination of causal relationships and pathways in clinical research, particularly treatment studies, and (3) PROs in clinical and public health applications – the development, validation, assessment, analysis, and reporting of PROs among various populations, especially vulnerable populations.
Accomplishments
Elected Fellow, American Medical Informatics Association
2023
·
American Medical Informatics Association
Exceptional Reviewer, Journal of Rural Health
2019
·
The Journal of Rural Health
Exemplary Teacher Award, University of Florida College of Medicine
2019
·
University of Florida College of Medicine
UF Health Shands Rose Rivers Chrysalis Award for Evolving Research
2019
·
UF Health
Travel Award, The South Big Data Hub
2016
·
The South Big Data Hub
Program Fellowship
2004
·
Ohio State University, Ohio State Biochemistry Program
Teaching Profile
Courses Taught
2015-2018,2020-2025
GMS6822 Measuring and Analyzing Health Outcomes II
2019
GMS6812 Health Outcomes Research in Cancer
2017-2018
NGR7979 Advanced Research
2018
GMS7979 Advanced Research
2018
GMS7980 Research for Doctoral Dissertation
2018
NGR7980 Research for Doctoral Dissertation
Research Profile
https://scholar.google.com/citations?hl=en&user=wnHzFS8AAAAJ
Open Researcher and Contributor ID (ORCID)
0000-0003-0587-4105
Publications
Academic Articles
2025
Decision Readiness and Determinants of Kidney Replacement Therapy among Veterans with Advanced Chronic Kidney Disease
Clinical Journal of the American Society of Nephrology.
[DOI] 10.2215/cjn.0000000713.
2025
Developing a Computable Phenotype for Identifying Children, Adolescents, and Young Adults With Diabetes Using Electronic Health Records in the DiCAYA Network
Diabetes Care.
[DOI] 10.2337/dc24-1972.
2025
Inequities in palliative care delivery to patients with HIV and stage IV cancers in the United States (2004-2020)
JNCI Cancer Spectrum.
9(2)
[DOI] 10.1093/jncics/pkae118.
[PMID] 39579085.
2025
Race- and Ethnicity-Related Disparities in Predialysis Nephrology Care, Kidney Disease Education, and Home Dialysis Utilization
Journal of the American Society of Nephrology.
36(1):122-132
[DOI] 10.1681/asn.0000000000000489.
2025
Toward a Computable Phenotype for Determining Eligibility of Lung Cancer Screening Using Electronic Health Records
JCO Clinical Cancer Informatics.
(9)
[DOI] 10.1200/cci.24.00139.
2025
Untreated insomnia as a contributor to geographic disparities in risk for Alzheimer’s disease and related dementias
Sleep Health.
[DOI] 10.1016/j.sleh.2025.01.002.
2024
Body mass index changes and their association with SARS-CoV-2 infection: a real-world analysis
International Journal of Obesity.
48(12):1785-1792
[DOI] 10.1038/s41366-024-01628-x.
2024
Developing a computable phenotype for glioblastoma
Neuro-Oncology.
26(6):1163-1170
[DOI] 10.1093/neuonc/noad249.
[PMID] 38141226.
2024
Development and Validation of KRT Knowledge Instrument
Clinical Journal of the American Society of Nephrology.
19(7):877-886
[DOI] 10.2215/cjn.0000000000000472.
2024
Disparities in Utilization of Immune Checkpoint Inhibitor Therapy Among Older Patients With Advanced Non–Small Cell Lung Cancer: A SEER-Medicare Analysis
JCO Oncology Advances.
(1)
[DOI] 10.1200/oa.24.00008.
2024
Exploring the Relation between Contextual Social Determinants of Health and COVID-19 Occurrence and Hospitalization
Informatics.
11(1)
[DOI] 10.3390/informatics11010004.
2024
Identifying social determinants of health from clinical narratives: A study of performance, documentation ratio, and potential bias
Journal of Biomedical Informatics.
153
[DOI] 10.1016/j.jbi.2024.104642.
[PMID] 38621641.
2024
Using electronic health records to enhance surveillance of diabetes in children, adolescents and young adults: a study protocol for the DiCAYA Network
BMJ Open.
14(1)
[DOI] 10.1136/bmjopen-2023-073791.
[PMID] 38233060.
2023
A study of generative large language model for medical research and healthcare
npj Digital Medicine.
6(1)
[DOI] 10.1038/s41746-023-00958-w.
[PMID] 37973919.
2023
Challenges in Adopting Artificial Intelligence to Improve Healthcare Systems and Outcomes in Thailand
Healthcare Informatics Research.
29(3):280-282
[DOI] 10.4258/hir.2023.29.3.280.
[PMID] 37591683.
2023
Disparities Contributing to Late-Stage Diagnosis of Lung, Colorectal, Breast, and Cervical Cancers: Rural and Urban Poverty in Florida
Cancers.
15(21)
[DOI] 10.3390/cancers15215226.
[PMID] 37958400.
2023
Does the Intersectionality of Race/Ethnicity and Type 2 Diabetes Increase the Odds of a Cervical Cancer Diagnosis? A Nested Case–Control Study of a Florida Statewide Multisite EHR Database
Healthcare.
11(13)
[DOI] 10.3390/healthcare11131863.
[PMID] 37444697.
2023
Impact of Contextual-Level Social Determinants of Health on Newer Antidiabetic Drug Adoption in Patients with Type 2 Diabetes
International Journal of Environmental Research and Public Health.
20(5)
[DOI] 10.3390/ijerph20054036.
[PMID] 36901047.
2023
Predicting the Risk of Alzheimer’s Disease and Related Dementia in Patients with Mild Cognitive Impairment Using a Semi-Competing Risk Approach
Informatics.
10(2)
[DOI] 10.3390/informatics10020046.
[PMID] 38919750.
2023
The role of health system penetration rate in estimating the prevalence of type 1 diabetes in children and adolescents using electronic health records
Journal of the American Medical Informatics Association.
31(1):165-173
[DOI] 10.1093/jamia/ocad194.
[PMID] 37812771.
2023
Unraveling Racial Disparities in Supportive Care Medication Use among End-of-Life Pancreatic Cancer Patients: Focus on Pain Management and Psychiatric Therapies
Cancer Epidemiology, Biomarkers & Prevention.
32(12):1675-1682
[DOI] 10.1158/1055-9965.epi-23-0251.
2022
Biases in using social media data for public health surveillance: A scoping review.
International journal of medical informatics.
164
[DOI] 10.1016/j.ijmedinf.2022.104804.
[PMID] 35644051.
2022
Personalised Lung Cancer Screening (PLuS) study to assess the importance of coexisting chronic conditions to clinical practice and policy: protocol for a multicentre observational study
BMJ Open.
12(6)
[DOI] 10.1136/bmjopen-2022-064142.
[PMID] 35732383.
2022
Procedural complications associated with invasive diagnostic procedures after lung cancer screening with low-dose computed tomography.
Lung cancer (Amsterdam, Netherlands).
165:141-144
[DOI] 10.1016/j.lungcan.2021.12.020.
[PMID] 35124410.
2022
Protocol for the development of a reporting guideline for causal and counterfactual prediction models in biomedicine
BMJ Open.
12(6)
[DOI] 10.1136/bmjopen-2021-059715.
[PMID] 35725267.
2022
Syndromic Surveillance Systems for Mass Gatherings: A Scoping Review
International Journal of Environmental Research and Public Health.
19(8)
[DOI] 10.3390/ijerph19084673.
[PMID] 35457541.
2022
The Impact of Race–Ethnicity and Diagnosis of Alzheimer’s Disease and Related Dementias on Mammography Use
Cancers.
14(19)
[DOI] 10.3390/cancers14194726.
[PMID] 36230648.
2021
Bagged random causal networks for interventional queries on observational biomedical datasets.
Journal of biomedical informatics.
115
[DOI] 10.1016/j.jbi.2021.103689.
[PMID] 33548542.
2021
Dental practitioners’ use of health risk assessments for a variety of health conditions
The Journal of the American Dental Association.
152(1):36-45
[DOI] 10.1016/j.adaj.2020.09.003.
[PMID] 33276954.
2021
The application of artificial intelligence and data integration in COVID-19 studies: a scoping review
Journal of the American Medical Informatics Association.
28(9):2050-2067
[DOI] 10.1093/jamia/ocab098.
[PMID] 34151987.
2021
The role of sex and rurality in cancer fatalistic beliefs and cancer screening utilization in Florida.
Cancer medicine.
10(17):6048-6057
[DOI] 10.1002/cam4.4122.
[PMID] 34254469.
2020
Causal inference and counterfactual prediction in machine learning for actionable healthcare
Nature Machine Intelligence.
2(7):369-375
[DOI] 10.1038/s42256-020-0197-y.
2020
Objective and subjective socioeconomic status associated with metabolic syndrome severity among African American adults in Jackson Heart Study.
Psychoneuroendocrinology.
117
[DOI] 10.1016/j.psyneuen.2020.104686.
[PMID] 32361636.
2019
ALOHA: developing an interactive graph-based visualization for dietary supplement knowledge graph through user-centered design
Bmc Medical Informatics and Decision Making.
19(4):1-18
2019
Assessing the effect of data integration on predictive ability of cancer survival models
.
2019
Association of Rates of Smoking During Pregnancy With Corporate Tobacco Sales Policies
Jama Pediatrics.
173(3):284-286
2019
Classification Tree Analysis of Factors Associated with Oral Cancer Exam
American Journal of Health Behavior.
43(3):635-647
2019
Facilitation or Hindrance: Physicians’ Perception on Best Practice Alerts (BPA) Usage in an Electronic Health Record System.
Health communication.
34(9):942-948
[DOI] 10.1080/10410236.2018.1443263.
[PMID] 29485296.
2019
Low Rates of Patient-Reported Physician–Patient Discussion about Lung Cancer Screening among Current Smokers: Data from Health Information National Trends Survey
.
28(5):963-973
2019
Low Rates of Patient-Reported Physician–Patient Discussion about Lung Cancer Screening among Current Smokers: Data from Health Information National Trends Survey
Cancer Epidemiology, Biomarkers & Prevention.
28(5):963-973
[DOI] 10.1158/1055-9965.epi-18-0629.
2019
Statistical thinking, machine learning
.
2019
The Wellness Incentive and Navigation intervention improved health-related quality of life among Medicaid enrollees: A randomized pragmatic clinical trial.
Health services research.
54(6):1156-1165
[DOI] 10.1111/1475-6773.13235.
[PMID] 31642066.
2018
A 3-minute test of cardiorespiratory fitness for use in primary care clinics.
PloS one.
13(7)
[DOI] 10.1371/journal.pone.0201598.
[PMID] 30059539.
2018
An ontology-guided semantic data integration framework to support integrative data analysis of cancer survival.
BMC medical informatics and decision making.
18(Suppl 2)
[DOI] 10.1186/s12911-018-0636-4.
[PMID] 30066664.
2018
Assessing the added predictive ability of a metabolic syndrome severity score in predicting incident cardiovascular disease and type 2 diabetes: the Atherosclerosis Risk in Communities Study and Jackson Heart Study.
Diabetology & metabolic syndrome.
10
[DOI] 10.1186/s13098-018-0344-3.
[PMID] 29796112.
2018
Dental Visits Mediate the Impact of Smoking on Oral Health
American Journal of Health Behavior.
42(1):59-68
[DOI] 10.5993/AJHB.42.1.6.
2018
Evaluating the reliability and validity of SF-8 with a large representative sample of urban Chinese
Health and Quality of Life Outcomes.
16(1)
[DOI] 10.1186/s12955-018-0880-4.
[PMID] 29615060.
2018
Metabolic syndrome severity is significantly associated with future coronary heart disease in Type 2 diabetes.
Cardiovascular diabetology.
17(1)
[DOI] 10.1186/s12933-017-0647-y.
[PMID] 29351794.
2018
New-Onset Diabetes Educator to Educate Children and Their Caregivers About Diabetes at the Time of Diagnosis: Usability Study
JMIR Diabetes.
3(2)
[DOI] 10.2196/diabetes.9202.
[PMID] 30291069.
2018
OC-2-KB: integrating crowdsourcing into an obesity and cancer knowledge base curation system.
BMC medical informatics and decision making.
18(Suppl 2)
[DOI] 10.1186/s12911-018-0635-5.
[PMID] 30066655.
2017
Assessing the Quality of Mobile Exercise Apps Based on the American College of Sports Medicine Guidelines: A Reliable and Valid Scoring Instrument
Journal of Medical Internet Research.
19(3)
[DOI] 10.2196/jmir.6976.
[PMID] 28270378.
2017
Comparing and Contrasting A Priori and A Posteriori Generalizability Assessment of Clinical Trials on Type 2 Diabetes Mellitus.
AMIA … Annual Symposium proceedings. AMIA Symposium.
2017:849-858
[PMID] 29854151.
2017
Data Integration through Ontology-Based Data Access to Support Integrative Data Analysis: A Case Study of Cancer Survival.
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine.
2017:1300-1303
[DOI] 10.1109/BIBM.2017.8217849.
[PMID] 29707415.
2017
Exploring the Association Between Self-Reported Asthma Impact and Fitbit-Derived Sleep Quality and Physical Activity Measures in Adolescents
JMIR mHealth and uHealth.
5(7)
[DOI] 10.2196/mhealth.7346.
[PMID] 28743679.
2017
Mobile Device Accuracy for Step Counting Across Age Groups
JMIR mHealth and uHealth.
5(6)
[DOI] 10.2196/mhealth.7870.
[PMID] 28659255.
2017
Using Social Media Data to Understand the Impact of Promotional Information on Laypeople’s Discussions: A Case Study of Lynch Syndrome
Journal of Medical Internet Research.
19(12)
[DOI] 10.2196/jmir.9266.
[PMID] 29237586.
2016
Validation of the Stroke and Aphasia Quality of Life Scale in a multicultural population.
Disability and rehabilitation.
38(26):2584-92
[DOI] 10.3109/09638288.2016.1138551.
[PMID] 26860472.
Education
M.S. in Biostatistics
2010
·
Ohio State University
Ph.D. in Bioinformatics
2009
·
Ohio State University
B.S. in Biotechnology
2002
·
Wuhan University
Contact Details
Phones:
- Business:
- (352) 294-5969
Emails:
- Business:
- yiguo@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100147
GAINESVILLE FL 32610 - Business Street:
-
1889 MUSEUM RD STE 7000 FL 7
GAINESVILLE FL 32611